Delaware Health Alert Network #296
January 30, 2013 12:13 pm
Health
Alert
DPH GUIDANCE ON TREATMENT OF SEXUALLY TRANSMITTED DISEASES DURING DOXYCYCLINE SHORTAGE
Background
On January 18, 2013 the Food and Drug Administration (FDA) reported a shortage of Doxycycline. Doxycycline is a recommended and frequently used therapy for common sexually transmitted diseases and associated syndromes. Doxycycline tablets/capsules are currently available in very limited supplies.
Recommendations
CDC recommendations and alternative regimens are listed below and also outlined at: http://www.cdc.gov/std/treatment/doxycyclineShortage.htm.
Chlamydia and Nongonococcal urethritis
- Azithromycin 1 g orally in a single dose
Gonorrhea
- Ceftriaxone 250 mg IM in a single dose and Azithromycin 1 g orally in a single dose
Syphilis (In penicillin allergic non-pregnant patients only)
- Primary or secondary syphilis: Tetracycline 500 mg orally four times daily for 14 days
- Late latent syphilis: Tetracycline 500 mg orally four times daily for 28 days
Epididymitis
- Ceftriaxone 250 mg IM in a single dose and Tetracycline 500 mg four times daily for 10 days
Pelvic Inflammatory Disease*
- Ceftriaxone 250 mg IM in a single dose and Clindamycin 450 mg orally four times daily for 14 days, with or without Metronidazole 500 mg orally twice a day for 14 days
*see STD Treatment Guidelines at http://www.cdc.gov/std/treatment/2010/default.htm for additional regimens.
Additional Information
- For additional information about the availability of Doxycycline, visit the FDA drug shortage website at: http://www.fda.gov/Drugs/DrugSafety/DrugShortages/ucm050792.htm
- For additional information about this or any other STD or to report a case, call the DPH Sexually Transmitted Disease Program at 302-744-1050 or visit our web page at: http://www.dhss.delaware.gov/dph/dpc/stds.html
******************
You are receiving this message because you are a registered member of the Delaware Health Alert Network. If you are not a member and would like to subscribe, please register at https://healthalertde.org
Categories of Health Alert messages:
- Health Alert: Conveys the highest level of importance; warrants immediate action or attention.
- Health Advisory: Provides important information for a specific incident or situation; may not require immediate action.
- Health Update: Provides updated information regarding an incident or situation; unlikely to require immediate action.