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Delaware Health Alert Network #254

July 20, 2011 3:24pm


Health Advisory
CEPHALOSPORIN SUSCEPTIBILITY AMONG NEISSERIA GONORRHOEAE ISOLATES

The Delaware Division of Public Health alerts the medical community of recently published information regarding Cephalosporin Resistant Gonorrhea.

The CDC is now seeing concerning patterns of decreased susceptibility to Cephalosporins in the treatment of gonorrhea (see http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6026a2.htm)

Although treatment failure has not been reported in the United States, decreased susceptibility and treatment failures documented in Asia, Norway & Japan, coupled with this organism’s ability to mutate and become resistant, raises possibilities that treatment failures are on the horizon in the United States.

Health care providers need to be aware of the potential for future resistance and take these important steps to ensure successful treatment outcomes for their patients:

  1. Treat.  Promptly, according to CDC recommendations. Health-care providers should use dual-therapy, ceftriaxone and azithromycin for the treatment of uncomplicated gonorrhea.
  2. Culture.  If a patient has suspected or documented treatment failure obtain an isolate to test for susceptibility.
  3. Report suspected treatment failure.  Treatment failure should be reported to the Division of Public Health, STD Program at (302) 744-1025.

For Additional Information about this or any other STD or to report a case, call the Delaware Division of Public Health, Sexually Transmitted Disease Program at (302) 744-1050 or visit our website at: http://www.dhss.delaware.gov/dhss/dph/dpc/stds.html.

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